13,866 research outputs found

    Introduction: Analytic, Continental and the question of a bridge

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    This is the peer reviewed version of the following article: Introduction: Analytic, Continental and the question of a bridge, which has been published in final form at 10.1177/1474885115582078. This article may be used for non-commercial purposes in accordance with SAGE’s Terms and Conditions for Self-Archiving.In philosophy and political theory, divisions come and go, but some persist despite beingobviously problematic. The analytic and Continental divide is one such division. Inpolitical philosophy and political theory, the division has been particularly pronounced.Analytic and Continental thinkers are divided not only over substantial issues but also over the very nature of political theorising. In spite of this fundamental nature, theorists often seem to assume that, as a division, the analytic/Continental divide requires no explanation. We suggest that, as a central division within political theory, and despite being acknowledged as problematic for quite some time, it has persisted because it has not been adequately examined. Once examined, the division turns out to be operationally weaker than it once was. In recent years, there has been a growing interest in engaging thinkers from the other side. This has been accompanied by a corresponding tendency, among both analytic and Continental philosophers and political thinkers, to reflect on the nature of their own tradition and ‘philosophy’. Both traditions have entered a self-conscious period of meta-reflection. Such questioning indicates the possibility of transformation within both groups, in the absence of settled frameworks and divisions. However, it is also clear that such signs are the beginning of the possibility of a new relation rather than a sign of the eclipse of the division. The continued institutional separation and the space between their respective philosophical vocabularies suggest that, while the time is ripe for work here, there is still much to be done

    Activation of type II calcium/calmodulin-dependent protein kinase by Ca^(2+)/calmodulin is inhibited by autophosphorylation of threonine within the calmodulin-binding domain

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    It is now well established that autophosphorylation of a threonine residue located next to each calmodulin-binding domain in the subunits of type II Ca^(2+)/calmodulin-dependent protein kinase causes the kinase to remain active, although at a reduced rate, after Ca^(2+) is removed from the reaction. This autophosphorylated form of the kinase is still sensitive to Ca2+/calmodulin, which is required for a maximum catalytic rate. After removal of Ca^(2+), new sites are autophosphorylated by the partially active kinase. Autophosphorylation of these sites abolishes sensitivity of the kinase to Ca^(2+)/calmodulin (Hashimoto, Y., Schworer, C. M., Colbran, R. J., and Soderling, T. R. (1987) J. Biol. Chem. 262, 8051-8055). We have identified two pairs of homologous residues, Thr^(305) and Ser^(314) in the alpha subunit and Thr^(306) and Ser^(315) in the beta subunit, that are autophosphorylated only after removal of Ca^(2+) from an autophosphorylation reaction. The sites were identified by direct sequencing of labeled tryptic phosphopeptides isolated by reverse-phase high pressure liquid chromatography. Thr^(305-306) is rapidly dephosphorylated by purified protein phosphatases 1 and 2A, whereas Ser^(314-315) is resistant to dephosphorylation. We have shown by selective dephosphorylation that the presence of phosphate on Thr^(305-306) blocks sensitivity of the kinase to Ca^(2+)/calmodulin. In contrast, the presence of phosphate on Ser^(314-315) is associated with an increase in the Kact for Ca^(2+)/calmodulin of only about 2-fold, producing a relatively small decrease in sensitivity to Ca^(2+)/calmodulin

    Practice in Reversing Judgments N.O.V., and in Amending the Pleading in Pennsylvania

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    The Trial of Cases in Pennsylvania

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    Crushed Stone in Indiana

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    During the field seasons of 1947 and 1948, two field parties of the Division of Geology, Indiana Department of Conservation, examined, sampled and mapped the quarries that are producing crushed stone in Indiana. Although the purpose of the survey was to study only active quarries, some inactive ones which seemed likely to resume operations were studied

    Alien Registration- Patton, Helena B. (Boothbay Harbor, Lincoln County)

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    https://digitalmaine.com/alien_docs/13178/thumbnail.jp

    Spectacular Elevations of Serum Alkaline Phosphatase: Clinical and Pathological Correlation Roy B.

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    The diseases responsible for extremely high serum alkaline phosphatase aclivily in 45 patients were proliferative bone disease (10 patients) and hepato-biliary tract disease (35 patients). Conditions found in these patients that are not usually thought to cause such high phosphatase levels were: drug-induced cholestasis (6 patients), non-malignant extra-hepatic bile duct obstruction (3 patients), biliary or portal cirrhosis (5 patients), and primary hyperparathyroidism with generalized osteitis fibrosa (1 patient)

    Crystallized intelligence and openness to experience: Drawing on intellectual-investment theories to predict job performance longitudinally

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    Various approaches to conceptualizing and measuring intelligence have been utilized throughout history. Despite the plethora of intelligence theories, the field of industrial and organizational (I-O) psychology has been largely dominated by the psychometric tradition of intelligence and Spearman\u27s general factor theory of intelligence (g). Moreover, other approaches to intelligence (e.g., the developmental perspective) have generally been ignored by I-O psychology. This is puzzling given the widespread acceptance among I-O psychologists of intelligence\u27s substantial and increasing importance in the modern workplace. Supported by a vast amount of research, g has often been recognized as the single best predictor of job performance. However, traditional measures of g have reached a plateau in terms of predictive validity for work-related criteria. Although g is not the sole determinate of job performance, failing to incorporate advancements from other fields (e.g., developmental psychology, cognitive psychology) is a potential limitation to continued improvement of job-performance prediction. One modern approach to intelligence that holds promise for improving our prediction of performance in the workplace is known collectively as the intellectual-investment theories, which posit that intellectual development is partially influenced by investment traits (e.g., Openness to Experience) that guide how, where, and when individuals invest their cognitive ability

    Computer Engineering Course for K-12 Teachers Assisted by First-Year ECE Undergrads

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    A sophomore-level course will be designed that introduces computer engineering fundamentals to pre-service science and math teachers in a highly interactive, hands-on environment, using active, cooperative learning methods. In cooperation with existing efforts, it will also be adapted to appeal to in-service teachers seeking a Masters degree in science or math education. It will illustrate how to use microprocessor based, mini-data acquisition systems, and robotics to create projects demonstrating physics and math concepts satisfying the Maine Learning Results and other national education standards. These materials will be distributed over the web. A unique aspect of this effort will be the recruitment and engagement of honors-level first-year Electrical and Computer Engineering and pre-service College of Education students to help develop curricular content that will interest middle and high school students. In-service teachers will be included in the development of pedagogy that efficiently conveys the engineering material to future science and math teachers. This project will introduce the engineering application of science and math, as well as providing a bridge between such informal science innovations as First Robotics, First Lego League, Bot Ball, etc. and the classroom environment. The major benefit, however, to the engineering establishment will be the application of and emphasis on engineering concepts to the science/math K-12 infrastructure. Through this course, pre-service and in-service teachers will be equipped with the tools to illustrate engineering principles and how they relate to concepts normally taught in conventional science and math courses

    Crushed Stone in Indiana

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    Indiana Geological Survey Report of Progress 3During the field seasons of 1947 and 1948, two field parties of the Division of Geology, Indiana Department of Conservation, examined, sampled, and mapped the quarries that are producing crushed stone in Indiana. In 1947 the parties were led by George E. Ericksen and the writer and in 1948 by Carroll N. Roberts and the writer. Field assistants for the first year were Robert Stewart and Dallas Fiandt. For 1948 field assistants were W. E. Taylor and Richard Erd. Although the purpose of the survey was to study only active quarries, some inactive ones which seemed likely to resume operations were studied. Of the 92 quarries shown on the map, 89 were in operation during the time of the field examination, and 3 have since become active. These 3 quarries have not been sampled or mapped, but they have been located, and the geological formations from which they produce have been ascertained. The samples are being analyzed by the chemical and spectrographic laboratories of the Division of Geology. A report containing comprehensive information on the limestone and dolomite resources of Indiana will be published when sufficient analyses are available to show regional chemical characteristics and variations of the formations. The report will include analyses of several other formations which have commercial potentialities but are not being exploited at this time. Active quarries are not properly distributed for a determination of the regional characteristics of some of the formations. In such cases, field parties will sample and examine the limestones in areas selected to fill out a well-spaced grid of control. These supplementary samples will be taken from natural outcrops, cuts, and .abandoned quarries during the field season of 1950. In the driftless area of south central Indiana and in most of the portions of southeastern and southwestern Indiana which are covered by Illinoian glacial drift, bedrock is close enough to the surface to permit economical stripping and quarrying. Between the outer border of the Wisconsin drift sheet and the lower portion of the area covered by the Champaign morainic system, major streams and some tributaries out through the glacial drift to bedrock and permit quarrying without excessive stripping. The quarries in Wayne, Rush, Shelby, Bartholomew, Putnam, Montgomery, and northwestern Decatur Counties (Plate 1) are within and near the margin of Wisconsin drift. In northern Indiana overburden is thin only in the valleys of major streams and at a few places in the till plains. The operator therefore quarries limestone and dolomite where they are available and has little opportunity to select his quarry site from a wide range of possible locations. In the limestone areas of southern Indiana, however, potential quarry sites are numerous, and the quarry operator may select a location upon the basis of convenience, geographic advantage, stripping conditions, and character of the limestone. The Silurian and Devonian formations in northern Indiana have not been precisely correlated with those in southern Indiana. The two areas have been treated separately in most geologic reports and are so treated here.Indiana Department of Conservatio
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